Pooja Kumari Pooja Kumari Asked 4 months ago

Does isotretinoin cause weight loss?

I recently started taking Isotretinoin for my skin. I've actually noticed I've lost a little weight since then, and I'm wondering if the medicine could be making me lose weight.

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5 answers

Divya Rao Divya Rao Joined Jan 2026 4 months ago
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I haven't heard of isotretinoin causing direct weight loss, but it can definitely affect your appetite or cause mild nausea sometimes. Since I have PCOS, I monitor my weight closely. If you are losing weight rapidly, it is best to discuss it with your dermatologist.

Sanjay Malhotra Sanjay Malhotra Joined Feb 2026 4 months ago

Don't worry too much about this. Sometimes the fatigue or dry mouth from isotretinoin can make you eat a bit less, leading to minor weight changes. Just focus on eating balanced meals and keeping yourself well hydrated.

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Nisha Chawla Nisha Chawla Joined May 2026 4 months ago

I wish it caused some weight loss for me, but unfortunately, my weight stayed exactly the same! The only thing I lost on isotretinoin was the moisture on my lips and my sleep due to itching. It's probably just a temporary change in your appetite.

Aravind Swamy Aravind Swamy Joined Jul 2026 4 months ago

My grandmother told me to have more curd rice and coconut water because this medicine creates too much heat in the body, which might reduce appetite. However, my doctor said weight loss is not a standard side effect. Do consult your doctor to be safe.

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Rohan Deshmukh Rohan Deshmukh Joined Jul 2026 4 months ago

Isotretinoin is a very strong drug that affects your liver enzymes. Unexplained weight loss could be a sign of systemic issues or liver stress, so please get a proper Liver Function Test (LFT) done and show the reports to your doctor immediately.

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