Kiran Joshi Kiran Joshi Asked 6 months ago

Can amitriptyline cause weight loss?

I've just started amitriptyline for chronic nerve pain. My doctor didn't mention anything about weight changes, but I'm curious if it can cause weight loss as a side effect.

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5 answers

Sanya Malhotra Sanya Malhotra Joined Feb 2026 6 months ago
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Honestly, I was actually expecting to lose some weight when I started this, but I feel like my appetite has only gone up. Did anyone else here actually drop weight on amitriptyline, or is it just me? I am constantly checking the scale and getting so anxious about these changes.

Karan Johar Karan Johar Joined Jun 2026 4 months ago

Don't panic at all, yaar! I also freaked out when my weight started fluctuating slightly in the first couple of weeks after starting it. I called my doc in a sweat, but they explained that minor appetite shifts are totally normal initially. It settled down soon, so just give your body some time to adjust.

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Rahul Deshmukh Rahul Deshmukh Joined Mar 2026 6 months ago

I can only speak for myself, but my doctor put me on this last year for my chronic nerve pain. Instead of weight loss, I actually ended up putting on about 4 kgs in two months because of late-night cravings. Everyone's body reacts so differently to these psychiatric meds.

Ananya Nair Ananya Nair Joined Apr 2026 6 months ago

Usually, amitriptyline is known to increase appetite, but I have seen some folks on my HealthifyMe community track a slight drop initially due to mild nausea. I'd suggest logging your daily calorie intake and weight on an app for a week. If the downward trend continues, just share those logs with your physician.

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Ganga Prasad Ganga Prasad Joined Apr 2026 6 months ago

Beta, medicines can do strange things to our body. I have seen people getting a bit of dry mouth or loose motion in the beginning, which might cause weight loss. Just eat healthy ghar ka khaana and don't take any tension, but do tell your doctor if you feel very weak.

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