Shreya Rao Shreya Rao Asked 8 months ago

Which antipsychotics cause the most weight gain?

My friend is struggling with significant weight gain since starting her antipsychotic medication. She's really worried about it. We were discussing which antipsychotics are known to cause the most weight gain, so she can perhaps discuss options with her doctor.

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5 answers

Rohan Deshmukh Rohan Deshmukh Joined Jun 2026 4 months ago
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Yaar, this is a tricky one. Actually, it's generally known that some older generation ones and even certain newer ones like Olanzapine (Zyprexa) and Quetiapine (Seroquel) can cause significant weight gain. But individual reactions vary a lot, so always discuss with your psychiatrist. They'll know your case best.

Sarita Singh Sarita Singh Joined Jan 2026 8 months ago

This is a very serious concern with antipsychotics. My friend had some complications related to medication side effects, which highlighted how crucial it is to monitor. Please, if you or someone you know is taking these, have a detailed discussion with their doctor about potential weight gain and metabolic health. It needs careful management.

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Rohit Kumar Rohit Kumar Joined Mar 2026 8 months ago

Yeah, I've heard Olanzapine and stuff like that can really pack on the pounds for some people. My cousin was on something similar, and he had to work extra hard to manage his weight. But everyone's body is different, so it's always best to get the real info from your psychiatrist, not just from what people say.

Karan Puri Karan Puri Joined May 2026 6 months ago

From a fitness perspective, weight gain from medication is tough, because it's not just about calories. Antipsychotics can really mess with metabolism. Some like Olanzapine are pretty notorious. If you're on them, definitely discuss diet and exercise strategies with your doctor and maybe a nutritionist too, if approved by doc.

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Vivek Sharma Vivek Sharma Joined Jul 2026 4 months ago

Antipsychotics are potent medications, and weight gain is a known side effect for many of them. Olanzapine and clozapine are often cited as having the highest risk. But you absolutely must confirm this with the prescribing psychiatrist. Ask them directly about the metabolic side effects and monitoring plans.

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