Does sulfasalazine cause weight gain?

I was recently prescribed this medicine and I am a bit worried about my weight. Has anyone here actually gained a lot of weight because of sulfasalazine, or is it mostly safe?

I check my weight every morning and panic if there is even a minor shift. Theoretically, sulfasalazine shouldn't cause weight gain, but fluid retention can sometimes happen. Please talk to your doc to ease your anxiety, it helped me sleep better.

I have used sulfasalazine for my colitis for over five years now. In my experience, it never caused any direct weight gain. Any slight change is usually just your appetite returning to normal once your inflammation goes down.

Look, sulfasalazine is not a steroid, so it won't puff you up. If you are gaining weight, look at your daily diet and lack of activity. Keep eating clean and keep moving, simple.

Unlike systemic steroids, sulfasalazine is not typically associated with weight gain in clinical studies. However, if you notice rapid swelling or weight changes, it is best to consult your treating physician to rule out any fluid retention issues.

Usually, sulfasalazine does not cause weight gain. If you are experiencing it, it might be due to other concurrent medications like steroids.

I actually lost weight due to my illness flare-up, and once I started sulfasalazine and felt better, I gained back my healthy weight. It wasn't the medicine making me fat, it just restored my normal health. Don't worry too much.