Tanvi Shah Tanvi Shah Asked 7 months ago

Does prometrium cause weight gain?

My doctor just prescribed Prometrium for my uterine fibroids. I'm already concerned about my weight, and I've read some reviews online saying it can cause weight gain. Is this a common side effect of Prometrium?

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6 answers

Vikram Rathore Vikram Rathore Joined Feb 2026 7 months ago
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Hey, don't worry. Prometrium is progesterone, which can cause fluid retention and make you feel bloated, which feels like weight gain. It's a very common side effect of hormone therapy, so just take it easy on yourself and let your doctor know if it gets uncomfortable.

Sudha Murthy Sudha Murthy Joined Jun 2026 4 months ago

Yes, some women do notice a slight increase in weight or bloating while taking Prometrium. Please be gentle with yourself, as these hormonal adjustments usually settle down over time with your doctor's guidance.

Karan Malhotra Karan Malhotra Joined Mar 2026 7 months ago

My wife was on Prometrium and honestly, between her mood swings and my lack of sleep, we both ended up gaining weight from late-night comfort eating! It definitely causes bloating and increased appetite, so watch out for those sudden midnight cravings.

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Simran Johar Simran Johar Joined Jan 2026 7 months ago

Oh don't stress too much about the scale right now! Prometrium definitely makes most of us feel super bloated and heavy, but it is mostly just water weight. Just drink plenty of water, eat simple food, and let your body adapt to the hormones.

Aditya Sen Aditya Sen Joined Feb 2026 7 months ago

My partner took Prometrium for a few months and she definitely felt bloated and put on a couple of kilos. Her doctor told her it is mostly water retention and hormonal fluctuations, and it went down after she finished her course.

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Preeti Saxena Preeti Saxena Joined Apr 2026 6 months ago

I have been on Prometrium for just two weeks and my jeans are already feeling so tight. I feel so anxious looking at myself in the mirror. Did anyone else gain weight this quickly, or is it just me overthinking it?

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