Suresh Bhatia Suresh Bhatia Asked 8 months ago

Does pomalyst cause weight gain?

A friend of mine is taking Pomalyst for a medical condition. He's concerned because he feels like he's gaining weight since starting the medication. Is it true that Pomalyst causes weight gain?

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7 answers

Sanjay Kapoor Sanjay Kapoor Joined Jan 2026 8 months ago
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Actually, Pomalyst is more commonly known to cause weight loss or loss of appetite rather than weight gain. However, because it is often taken along with steroids like dexamethasone, those steroids can cause water retention and weight gain. Don't stop the medicine, just discuss these changes with your oncologist.

Ritu Verma Ritu Verma Joined Jan 2026 8 months ago

It can be confusing, but Pomalyst itself usually causes weight loss or nausea. But if you are gaining weight, it might be due to fluid retention or other companion medicines like steroids. Keep a track of any sudden swelling in your legs and let your doctor know.

Amit Saxena Amit Saxena Joined May 2026 5 months ago

Haan, Pomalyst ke sath weight changes ho sakte hain, par mostly logon ka weight kam hota hai nausea ki wajah se. Agar weight gain ho raha hai, toh ho sakta hai steroids ki wajah se ho jo iske sath milti hain na. Ek baar apne doctor se confirm kar lijiye.

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Consult a dietary specialist

Pooja Roy Pooja Roy Joined Jan 2026 8 months ago

Oh god, dealing with heavy medications like Pomalyst must be so stressful, and noticing weight changes only adds to the anxiety. I always get so worried about fluid retention or swelling. Please don't panic, but do mention this to your healthcare team so they can reassure you.

Karthik Subramanian Karthik Subramanian Joined Apr 2026 6 months ago

Weight fluctuations are common during chemotherapy regimens. Pomalyst usually causes weight loss, but associated medications can lead to weight gain due to bloating. Track your daily weight and share the log with your doctor during your next scheduled consult.

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Sanya Mirza Sanya Mirza Joined Mar 2026 8 months ago

I know how scary it is to see your body change when you are on strong medicines, it can make you feel so out of control. Pomalyst usually doesn't cause direct weight gain, but other factors in the treatment can. Please share your worries with your doctor, they will help you manage this.

Rohan Das Rohan Das Joined Jun 2026 5 months ago

My uncle is on Pomalyst and he actually lost weight because his appetite went down. If you're putting on weight, it is likely because of the steroids prescribed with it. Just talk to your oncologist directly, they'll explain why it's happening.

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