Sunita Iyer Sunita Iyer Asked 9 months ago

Can mesalamine cause weight gain?

I started taking mesalamine for my IBD a few months ago, and I've noticed I'm gaining weight. I'm trying to figure out if this medication could be a cause for my weight gain.

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7 answers

Amit Sen Amit Sen Joined Feb 2026 9 months ago
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Yes, some people do notice mild weight changes on this medication. It can sometimes be due to fluid retention or simply because your gut is healing and absorbing nutrients better. Please take care of yourself.

Priyanka Kapoor Priyanka Kapoor Joined Mar 2026 7 months ago

Actually, when my colitis got better with mesalamine, I was finally able to eat without pain! Naturally, I started enjoying my parathas and sweets again, which did cause some weight gain. Sometimes it's just your appetite returning after being sick!

Rohan Das Rohan Das Joined Mar 2026 7 months ago

I was looking this up because my cousin is on this drug. Interestingly, mesalamine itself doesn't typically cause direct weight gain like steroids do, but since it controls inflammation, patients start absorbing food much better and gain back lost weight.

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Nidhi Bhatia Nidhi Bhatia Joined Feb 2026 8 months ago

I completely understand how stressful it is to watch the scale go up when you're already dealing with a difficult gut issue. I used to obsess over every gram. But remember, gaining a little weight often means your body is finally recovering from inflammation.

Shalini Nair Shalini Nair Joined Jul 2026 4 months ago

It is so hard when your body changes and you feel like you've lost control over your weight. I struggled with my body image so much while on gut treatment. Just know that your worth is not defined by a number, and your body is trying its best to heal.

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Vijay Mallya Vijay Mallya Joined Jan 2026 9 months ago

If you notice sudden, rapid weight gain or swelling in your ankles while taking mesalamine, please check with your doctor immediately. It could sometimes indicate kidney issues or fluid retention which need professional evaluation. Don't ignore rapid changes.

Savitri Devi Savitri Devi Joined Mar 2026 7 months ago

Beta, jab pet ki bimari theek hoti hai na, toh sharir thoda bhaari hone lagta hai kyunki khana sahi se lagta hai. Chinta mat karo, yeh achhi baat hai ki aapka sharir tandurust ho raha hai. Bas khane-peene ka thoda dhyan rakho.

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