Suresh Patel Suresh Patel Asked 8 months ago

Can 25 mg of amitriptyline cause weight gain?

My doctor prescribed me 25 mg of amitriptyline for my chronic headaches, and I've been taking it for a few weeks now. I've noticed my weight increasing slightly, and I'm quite concerned about it. Is it possible for this medicine to cause weight gain?

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6 answers

Saraswathi Raman Saraswathi Raman Joined May 2026 5 months ago
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My daughter was prescribed amitriptyline 25 mg for her chronic migraines, and she did experience an increase in appetite and gained a few kilos. It definitely increases cravings, especially for sweets, so we had to be very practical about keeping healthy snacks around. Do monitor it and discuss with your doctor if it becomes a concern.

Karthik Subramanian Karthik Subramanian Joined Mar 2026 7 months ago

Yes, amitriptyline can cause weight gain even at a lower dose like 25 mg because it often increases cravings. My aunt advised me to eat fiber-rich foods like oats and fruits to manage the hunger, which helped a lot. However, please consult your doctor before making any changes to your medication.

Sanjay Mehra Sanjay Mehra Joined Jun 2026 4 months ago

At my age, even looking at a gulab jamun causes weight gain, but yes, amitriptyline 25 mg is notorious for making you crave carbs! I took it for sleep issues and noticed my waistband getting tighter within a month. Keep an eye on your late-night snacking, but don't stop the medicine without asking your doctor.

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Rohan Malhotra Rohan Malhotra Joined Jan 2026 8 months ago

Hey, don't stress too much about the weight gain! Amitriptyline can slow down your metabolism and boost your appetite a bit, even at 25 mg. Just focus on drinking plenty of water, staying slightly active, and if you feel it's getting out of hand, just have a friendly chat with your doc about alternatives.

Nisha Sen Nisha Sen Joined Feb 2026 8 months ago

Weight gain is indeed a known side effect of amitriptyline because of how it affects certain receptors in the body, but everyone reacts differently. Don't trust random internet diets or remedies to counter this. Speak directly to the doctor who prescribed it to you to get the correct advice.

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Rajesh Gupta Rajesh Gupta Joined Mar 2026 7 months ago

Yes, amitriptyline 25 mg can cause weight gain due to increased water retention and appetite. If you plan to manage this, focus on simple home-cooked meals instead of buying expensive diet plans or fat-burners. Budgeting for a simple monthly weight check and consulting your doctor is the most practical way forward.

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