Rahul Kumar Rahul Kumar Asked 6 months ago

Can i take ibuprofen after excedrin migraine?

I took Excedrin Migraine earlier for a headache, but it hasn't really helped. Is it okay to take ibuprofen now to see if that works better, or should I be concerned about combining them?

7

7 answers

Arjun Das Arjun Das Joined Jun 2026 4 months ago
Most liked

I tried taking ibuprofen right after Excedrin once because my head was splitting, and I got terrible stomach cramps. My doctor told me never to mix them without a proper gap.

Sneha Paul Sneha Paul Joined Mar 2026 6 months ago

I am not very sure, but doesn't Excedrin already have aspirin and paracetamol? Taking ibuprofen on top of that might be too strong for the stomach, right?

Rohan Mehta Rohan Mehta Joined Feb 2026 6 months ago

According to my health tracker's drug interaction guide, taking ibuprofen and Excedrin together increases the risk of stomach irritation and bleeding. You should consult a doctor before mixing them.

Powered by

Consult a neurologist

Anjali Sharma Anjali Sharma Joined Mar 2026 6 months ago

Taking both can be extremely harsh on an empty stomach. If you absolutely must take them, ensure you have eaten a proper meal first and check with your physician.

Rajesh Pillai Rajesh Pillai Joined May 2026 6 months ago

Both of these medications can affect your blood pressure and kidneys if combined. Please get a proper checkup and let your doctor prescribe a safe pain management plan.

Related reads

All articles
Siddharth Sen Siddharth Sen Joined May 2026 5 months ago

Excedrin already contains aspirin and paracetamol, so adding ibuprofen can lead to an accidental overdose of NSAIDs. It is definitely best to seek your doctor's advice on safe timing.

Harpreet Kaur Harpreet Kaur Joined May 2026 5 months ago

Don't load your body with so many heavy painkillers at once, it's not good for your liver and stomach. Keep a gap of at least 8 hours, or better, ask your doctor for a single safe tablet.

Evidence-based health, reviewed by clinicians. Free, weekly.